SAM D21 Arm® Cortex®-M0+ Microcontrollers

Microchip Technology SAM D21 Arm® Cortex®-M0+ Microcontrollers (MCUs) are low-power MCUs that range from 32- to 64-pins with up to 256KB Flash and 32KB of SRAM. The Microchip Technology SAM D21 MCUs have a maximum 48MHz frequency and reach 2.46 CoreMark/MHz. The devices are designed for simple and intuitive migration with identical peripheral modules. Features include hex-compatible code, identical linear address map, and pin-compatible migration paths between all devices in the product series. All devices include intelligent and flexible peripherals, an Event System for inter-peripheral signaling, and support for capacitive touch buttons, slider, and wheel user interfaces.

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Description Datasheet Availability Pricing (SGD) Filter the results in the table by unit price based on your quantity.
Qty. RoHS ECAD Model Series
Mounting Style
Package/Case
Core
Program Memory Size
Data Bus Width
ADC Resolution
Maximum Clock Frequency
Number of I/Os
Data RAM Size
Supply Voltage - Min
Supply Voltage - Max
Minimum Operating Temperature
Maximum Operating Temperature
Qualification
Packaging
Microchip Technology ARM Microcontrollers - MCU 48QFN,85C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
5,205In Stock
Cut Tape
$3.79
$3.67
Reel
$3.14
MouseReel Available
Min.: 1
Mult.: 1
: 4,000
SAMD21 SMD/SMT QFN-48 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 38 I/O 8 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP48, 128kFlash,T&R,USB, I Temp
Datasheet
1,308In Stock
Cut Tape
$4.12
$4.00
Reel
$3.40
Min.: 1
Mult.: 1
: 2,500
SAMD21 SMD/SMT TQFP-48 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 38 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape
Microchip Technology ARM Microcontrollers - MCU 48TQFP 125C, GREEN,1.6-3.6V,48MHz
Datasheet
1,265In Stock
Cut Tape
$6.32
$6.11
Reel
$5.21
MouseReel Available
Min.: 1
Mult.: 1
: 2,500
SAMD21 SMD/SMT TQFP-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 48TQFP GRN1.6-3.6V48MHz
Datasheet
1,599In Stock
$5.66
$5.14
$4.66
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray

Microchip Technology ARM Microcontrollers - MCU 128KB 16KB 64QFN GRN1.6-3.6V48MHz
Datasheet
2,402In Stock
$4.56
$4.12
$3.75
Min.: 1
Mult.: 1
SAMD21 SMD/SMT QFN-64 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 52 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU CM0, TQFP 64 , 128KFlash, USB, Extended Temp 125C, T&R
Datasheet
1,492In Stock
Cut Tape
$4.80
$4.62
Reel
$3.94
MouseReel Available
Min.: 1
Mult.: 1
: 1,500
SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 128 kB 32 bit 48 MHz 52 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU CM0,TQFP64, 128kFlash,Trays,USB, I Temp
Datasheet
516In Stock
$4.23
$3.82
$3.48
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 52 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 64TQFP 125C, GREEN,1.6-3.6V,48MHz
Datasheet
2,202In Stock
$6.56
$5.96
$5.40
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 52 I/O 32 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 64TQFP GRN1.6-3.6V48MHz
Datasheet
2,175In Stock
$5.96
$5.43
$4.88
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 52 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 128KB 16KB32TQFP GRN1.6-3.6V48MHz
Datasheet
751In Stock
$3.81
$3.47
$3.17
$3.16
$3.14
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 128KB 16KB32TQFP GRN1.6-3.6V48MHz
Datasheet
1,440In Stock
Cut Tape
$4.07
$3.94
Reel
$3.36
MouseReel Available
Min.: 1
Mult.: 1
: 2,000
SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32QFN 125C, GREEN,1.6-3.6V,48MHz
Datasheet
542In Stock
$4.11
$3.75
$3.40
Min.: 1
Mult.: 1
SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 128KB 16KB32QFN GRN1.6-3.6V48MHz
Datasheet
613In Stock
$3.90
$3.54
$3.20
Min.: 1
Mult.: 1
SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 26 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 64KB 8KB32TQFP GRN 1.6-3.6V 48MHz
Datasheet
687In Stock
$5.39
$4.88
$4.43
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 26 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 256KB 32QFN GRN 1.6-3.6V 48MHz
Datasheet
1,889In Stock
$5.26
$4.80
$4.35
Min.: 1
Mult.: 1
SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 26 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 48QFN 125C, GREEN,1.6-3.6V,48MHz
Datasheet
1,048In Stock
$4.35
$3.94
$3.58
Min.: 1
Mult.: 1
SAMD21 SMD/SMT QFN-48 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 38 I/O 16 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 128KB 16KB 48QFN GRN1.6-3.6V48MHz
Datasheet
2,000In Stock
4,000Expected 16/11/2026
Cut Tape
$4.07
$3.94
Reel
$3.35
MouseReel Available
Min.: 1
Mult.: 1
: 4,000
SAMD21 SMD/SMT QFN-48 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 38 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 48QFN GRN1.6-3.6V48MHz
Datasheet
2,184In Stock
$5.54
$5.03
$4.56
Min.: 1
Mult.: 1
SAMD21 SMD/SMT QFN-48 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 38 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray

Microchip Technology ARM Microcontrollers - MCU 64QFN,85C TEMP, GREEN, 3.3V, 48MHZ, T&R
Datasheet
3,520In Stock
Cut Tape
$4.01
$3.88
Reel
$3.32
MouseReel Available
Min.: 1
Mult.: 1
: 4,000
SAMD21 SMD/SMT QFN-64 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 52 I/O 8 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 128KB 16KB 64TQFP GRN1.6-3.6V48MHz
Datasheet
3,420In Stock
$4.23
$3.82
$3.48
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 128 kB 32 bit 12 bit 48 MHz 52 I/O 16 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 256KB 32KB 64TQFP GRN1.6-3.6V48MHz
Datasheet
2,594In Stock
Cut Tape
$6.07
$5.83
Reel
$5.02
MouseReel Available
Min.: 1
Mult.: 1
: 1,500
SAMD21 SMD/SMT TQFP-64 ARM Cortex M0+ 256 kB 32 bit 12 bit 48 MHz 52 I/O 32 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32QFN,85C TEMP, GREEN, 3.3V, 48MHZ
Datasheet
388In Stock
$3.03
$2.76
$2.50
Min.: 1
Mult.: 1
SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 26 I/O 4 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32QFN 125C, GREEN,1.6-3.6V,48MHz
Datasheet
63In Stock
$3.35
$3.03
$2.76
Min.: 1
Mult.: 1
SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 26 I/O 4 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Tray
Microchip Technology ARM Microcontrollers - MCU 32QFN 125C, GREEN,1.6-3.6V,48MHz,T&R
Datasheet
1,678In Stock
Cut Tape
$3.45
$3.36
Reel
$2.84
MouseReel Available
Min.: 1
Mult.: 1
: 5,000
SAMD21 SMD/SMT QFN-32 ARM Cortex M0+ 32 kB 32 bit 12 bit 48 MHz 26 I/O 4 kB 1.62 V 3.63 V - 40 C + 125 C AEC-Q100 Reel, Cut Tape, MouseReel
Microchip Technology ARM Microcontrollers - MCU 32TQFP,85C TEMP, GREEN, 3.3V, 48MHZ
Datasheet
318In Stock
$3.59
$3.25
$2.95
Min.: 1
Mult.: 1
SAMD21 SMD/SMT TQFP-32 ARM Cortex M0+ 64 kB 32 bit 12 bit 48 MHz 26 I/O 8 kB 1.62 V 3.63 V - 40 C + 85 C AEC-Q100 Tray